NOMASUST 250

NOMASUST-250

BLEND OF 4 TESTOSTERONES INJECTION 250mg/ml

COMPOSITION:

Each ml contains

Testosterone Propionate BP 30mg

Testosterone Phenylpropionate BP 60mg

Testosterone Isocaproate 60mg

Testosterone Decanoate BP 100mg

Benzyl Alcohol BP 5.0% v/v

Arachis oil BP q.s.

PHARMACOLOGICAL CLASSIFICATION:

Male sex hormones

HARMACOLOGICAL ACTION:

NOMASUST INJECTION is an androgenic preparation for intramuscular administration containing four different ester of the natural hormone testosterone

NDICATIONS :

Testosterone replacement therapy in male Hypogonadal disorders, for example:

-After Castration

-Eunuchoidism

- Hypopituitarism

Moreover, testosterone therapy may be indicated in osteoporosis due to Hypogonadal male androgen deficiency

CONTRA-INDICATIONS:

Known or suspected mammary or prostatic carcinoma in the intended for use in female patients

WARNINGS:

Middle-aged and elderly males with angina pectoris or other severe circulatory disease should receive androgen treatment only under very careful supervision

DOSAGE AND DIRECTIONS FOR USE:

In general, dosage should be adjusted according to the response of the individual patient. Usually, one injection of 1 ml per four weeks is adequate SUSTANBOLIN should be administered by deep intramuscular injection

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:

he following adverse reactions have been associated with androgen therapy:

-priapism and other signs of excessive sexual stimulation.

-In prepubertal boys : precocious sexual development.

An increased frequency of erections phallic enlargement and premature epiphyseal closure

-Oligospermia and decreased ejaculatory volume

-Water and salt retention

Precautions :

If androgen-associated adverse reactions occur, treatment should be interrupted and, after disappearance of the symptoms, be resumed at a lower dosage. Patients with latent or overt cardiac failure, renal dysfunction, hypertension migraine (or story of these conditions) should be monitored, since androgens may occasionally induce salt and fluid retention, Androgens should be used cautiously in prepubertal boys to avoid premature epiphyseal closure or precocious sexual development. A decrease in protein bound iodine (PBI) may occur, but this has no clinical significance

KNOWN SYMPTOMS OF OVER.DOSAGE AND PARTICULARS OF ITS TREATMENT:

See "Side-effects and Special Precautions". Treat symptomatically

STORAGE INSTRUCTIONS:

Store at room temperature <25 C, Protect from sunlight Keep out of reach of children!

PRESENTATION :

10 ml glass vial duly labeled&packed in a printed carton along with a leaflet. OR 10 Ampoules of 1 ml vial duly labeled & packed in a printed carton along with a leaflet.